A MIXTURE OF "CHEATS" AND "CO-OPERATORS" CAN ENABLE MAXIMAL GROUP BENEFIT.


FUNCTIONAL GENOMICS IDENTIFIES TIS21-DEPENDENT MECHANISMS AND PUTATIVE CANCER DRUG TARGETS UNDERLYING MEDULLOBLASTOMA SHH-TYPE DEVELOPMENT

We have recently generated a novel medulloblastoma (MB) mouse model with activation of the Shh pathway and lacking the MB suppressor Tis21 (Patched1+-Tis21KO).ts main phenotype is a defect of Juice migration of the cerebellar granule precursor cells (GCPs).By genomic analysis of GCPs in vivo, we identified as drug target and major responsible of th

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Genome wide profiling in oral squamous cell carcinoma identifies a four genetic marker signature of prognostic significance.

BACKGROUND:Cancers of the oral cavity are primarily oral squamous cell carcinomas (OSCCs).Many of the OSCCs present at late stages with an exceptionally poor prognosis.A probable limitation in management of patients with OSCC lies in the insufficient knowledge pertaining to the linkage between copy number alterations in OSCC and oral tumourigenesis

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Investigating the Impact of Museum Cultural and Creative Products on Consumers’ Cultural Interest: A Case Study of Dunhuang

This research aims to explore the impact of museum cultural and creative products on consumers’ cultural interest.Based on previous literature, this research proposed a research model to explore the crucial factors influencing consumers’ cultural interest.This research selected bookmarks from Dunhuang Museum’s cultural and crea

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Characterization of influenza A virus induced transposons reveals a subgroup of transposons likely possessing the regulatory role as eRNAs

Abstract Although many studies have observed genome-wide host transposon expression alteration during viral infection, Chair Beds the mechanisms of induction and the impact on the host remain unclear.Utilizing recently published influenza A virus (IAV) time series data and ENCODE functional genomics data, we characterized virus induced host differe

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